|Causes of mycosis fungoides is still not clear. To date, no known motives of uncontrolled T-cell proliferation. It is assumed that the occurrence of mycosis fungoides may be due to a viral infection. Thus, several studies reported the detection of a primary cell culture derived from the patient's lymph node-infiltrating plaque stage mycosis fungoides, viral particles, morphologically characteristic of retroviruses such as C. In addition, the DNA of primary cell cult... Read more »
|In the erythematous stage mycosis fungoides exhibit normal inflammatory infiltrate, but sometimes it contains a small number of reticular cells. In the plaque stage of infiltration is predominantly of papillary dermis. Characterized by a significant content in it eosinophils and the presence of unique, atypical reticular cells ("mycotic" yr), as well as "microabscesses" Rub (small accumulations in malpigievom node lymphocytes and histiocytes). In the tumor stage inc... Read more »
|The most common form of aliber - Bazin, which are divided into three stages: erythematous, plaque (infiltrative), and tumor. In the erythematous stage appear yellowish-pink or bluish-purple spots with light gray scaling, accompanied by very severe itching, which may precede the rash. Initially, the rash located on the trunk, extensor surfaces of limbs, and then merge and can capture large areas of skin. This stage often has a polymorphic pattern, and may remind many... Read more »
|It is believed that at the initial, favorable occurring forms of mycosis fungoides is expedient to appoint conservative restorative treatment (group B vitamins, vitamin C) and outer steroid ointment. It is also shown spa treatment.
In more severe stages of the disease is preferable to prescribe combination therapy: cytotoxic agents, anticancer antibiotics. It is advisable to combine prospidin with corticosteroids.
In these cases, the effect is faster... Read more »