Angiosarcoma of the liver (syn.: gemangioendotelioma, angioblasticheskaya sarcoma endotelioblastoma) - a rare, very malignant endothelial tumor that is difficult to differentiate from hepatocellular carcinoma.
Angiosarcoma of the liver usually occurs in men after 60 years. In the general population of tumor accounts for only 1.8% of all primary tumors of the liver and detected 30 times less frequently than hepatocellular carcinoma.
What triggers angios... Read more »
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Liver increased in size, contains a set of nodes, resembling cavernous hemangioma. Angiosarkomu belong to a group of diseases that occur with damage to the sinusoidal barrier, which also includes pelioz liver and dilatation of the sinuses. These three states can be linked to the toxic effects of vinyl chloride, arsenic, torotrasta and anabolic steroids. Angiosarcoma may complicate the course of neurofibromatosis.
For the characteristic distribution of angios... Read more »
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Symptoms of angiosarcoma of the liver are not specific. Patients complain of abdominal pain, weakness and weight loss, also often referred hepatomegaly, ascites and jaundice. Liver function tests are also changed, but none of them is not a direct marker of tumor. Thrombocytopenia and disseminated intravascular coagulation snndrom typical for angiosarcoma and may be associated with local factors influence tumor thrombus and blood elements. Massive bleeding into the a... Read more »
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Ultrasonography angiosarcoma are either single or multiple hyperechoic education, usually heterogeneous due to hemorrhage of different periods.
Computed tomography reveals a reticulated pattern torotrasta deposits in the liver, and spleen. Circular distribution of the substance on the periphery of the node is a characteristic feature of angiosarcoma. In the absence of deposits at non-enhanced CT torotrasta angnosarkomy appear as single or multiple gipodensny... Read more »
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Treatment angiosarkom is radical removal of the tumor. In this case the best chance to save lives gives amputation. However, even it does not prevent the development of relapses. Primary tumor is sensitive to radiation therapy, but its recurrence Roentgen resistant. Fatal outcome can sometimes be put off by chemotherapy. Metastasized angiosarcoma affecting the lungs, liver, bone, brain, difficult to treat and are a major cause of death.
Poor prognosis, only ... Read more »
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