Be treated as opposed to acute leukemia, a patient with chronic leukemia do not always immediate. Chronic leukemia progresses more slowly than acute leukemia, particularly chronic lymphocytic leukemia (CLL).
Methods for the treatment of chronic leukemia:
Observation period. Patients with chronic lymphocytic leukemia (CLL) in the early stages of treatment is not necessary. CLL often progresses very slowly and may be asymptomatic. The patient and doctor decide to refrain from treatment for a while. During this time, the patient is under medical supervision. It is believed that 1 in 3 patients with CLL do not require treatment.
Stem cell transplantation. Some of autologous transplantation, this means that stem cells from the patient's body (from the same organism) is applied. Some transplant - halogen, with the stem cells are cells of the donor. To destroy the purpose of transplantation to all cells in the bone marrow, including cancer cells and replace them with new, healthy cells.
Biological therapy. This use of special drugs that improve the natural defenses against cancer. One of these drugs are used in the treatment of chronic myeloid leukemia (CML), interferon-alpha.
Radiation therapy. The radiation exposure is used to destroy cancer cells. Radiation therapy can reduce enlarged lymph nodes and spleen. Sometimes the radiation exposure of the whole organism is used to treat chronic lymphocytic leukemia, or training the body to a bone marrow transplant.
Clinical trials conducted to evaluate the safety and efficacy of new drugs and therapies. People with chronic leukemia are diagnosed frequently involved in clinical trials.
Chemotherapy. The use of chemotherapeutic agents for cancer treatment.
The treatment of infectious diseases. Patients with chronic leukemia immune system is weakened, and the body can not fight against infectious diseases. The patient and the physician should zoster, the possibility of the occurrence of symptoms of communicable diseases such as pneumonia, fungal infections, herpes. Early diagnosis and treatment of these and other infectious diseases is very important. Notify certain infectious diseases such as influenza vaccine preventable diseases, are a vaccine against pneumonia. Patients with CLL should be examined regularly to identify other types of cancer. The risk of secondary cancers in patients with CLL before.
Chronic leukemia progresses despite treatment
For patients with advanced or recurrent form of chronic myeloid leukemia imatinib (Gleevec) can be used in combination with other medications. For patients, imatinib is not helped, it is now for a new drug called dasatinib (Sprisel), dasatinib (Sprycel) is available. Other new drugs in clinical trials.
In contrast to acute, chronic leukemia, blood cells to "mature" period, but the vast majority of the resulting cells are not able to direct their function. Therefore, a laboratory analysis can be seen fairly high number of white blood cells, although to protect the body against infection, they can not. In cases where the number of granulocyte-cells is so large that it interferes with the normal blood flow, patients have leykofarez, removing excess white blood cells, including tumor cells. The effect of this process rather quickly, though only temporarily.
Chronic leukemia life expectancy
To chemotherapy, life expectancy 57 years. Death occurs in chronic myelogenous leukemia in blast crisis period of infectious and haemorrhagic syndrome. The prognosis substantially influenced by the availability and sensitivity of the Philadelphia chromosome of the disease to therapy. The use of interferon-alpha significantly changed the prognosis for the better.
Chronic leukemia may not had the initial phase, 50% of patients with chronic leukemia, no complaints about her health, her leukemia was diagnosed after blood tests carried out on another occasion. Even after diagnosis, chronic leukemia can leak for years, relatively benign. This is called the phase of the monoclonal and is characterized by the presence of a clone of tumor cells. The next stage by the appearance of secondary tumors clones, characterized by a rapid course with the advent of several explosions and called poliklonovoy stage or the stage of blast crisis. Killed 80% of patients with chronic leukemia in blast crisis stage.
Developed as a result of the defeat of tumor cells in patients with chronic leukemia splenitis and hepatomegaly (enlargement of the spleen and liver), the total chronic anemia, generalized lymph nodes affected.
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