What is chondrosarcoma
Chondrosarcoma - a heterogeneous group of non-epithelial malignant tumors of cartilage.
The share of chondrosarcoma accounts for about 20-25% of bone sarcoma. This tumor occurs in adult... Read more » |
What triggers chondrosarcoma
The exact causes of primary chondrosarcoma is unknown. Most prone to malignant transformation of chondroma, bone and cartilaginous exostosis, hearths dishondroplazii.
Factors contributing to malignancy in the first place are the following:
• inadequate treatment, in particular the holding-saving resection ... Read more » |
Pathogenesis chondrosarcoma
Macroscopically highly differentiated chondrosarcoma resembles normal hyaline cartilage. Usually it has lobed structure. On the section is sometimes noticeable yellowish areas of calcification, kistovidnye cavity with mucoid content, the broad gelatinous zone. In highly malignant chondrosarcoma occurs as hemorrhagic necrosis. Central chondrosarcoma, reaches a... Read more » |
Symptoms of chondrosarcoma
Start malignancy clinically benign cartilaginous structures is difficult to establish because the disease has a long latency period. Progressive tumor growth, appearance and noticeable increase in pain give reason to suspect malignancy chondroma.
Chondrosarcoma of the pelvic bones often grow large and manifested ... Read more » |
Diagnosis of chondrosarcoma
For the diagnosis of chondrosarcoma may require different tests and studies. Usually, the X-ray painful area of bone is sufficient to identify a tumor. Other diagnostic procedures for cancer screening are often performed in order to verify the extent of the cancer spreading to other areas of the body.
... Read more » |
Treatment of chondrosarcoma
Most hondrosarkom resistant to chemotherapy, so the main treatment hondrosarkom is excision of the primary tumor and its metastases. However, this rule has two exceptions:
- De differentiated chondrosarcoma (highly differentiated tumors to have transformed into a malignant fibrous histiocytes or osteogenic sarcoma)... Read more » |
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