Aldosteronoma-tumor originating from cells of the glomerular zone of the adrenal cortex, privodyaschayu to the syndrome of primary hyperaldosteronism - Conn's syndrome. Benign adrenal tumors (adenomas) are a major cause of primary hyper aldosteronism, accounting for 70-85% of cases. Less than 5% of the tumors are malignant nature (malignant aldosteroma). Among other causes of primary hyperaldosteronism describe bilateral or unilateral hyperplasia of the adrenal cort... Read more »
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Clinical manifestations of the disease can be grouped in three major syndromes - cardiovascular, neuromuscular and kidney.
Cardiovascular syndrome i... Read more »
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In the diagnosis of the disease attach importance to high blood pressure combined with hypokalemia, giperkaliuriey, increased basal level of aldosterone in the blood and daily excretion, reduced plasma renin activity. Take into account the presence of hypernatremia, gipohloremicheskogo extracellular alkalosis, increased blood volume.
In difficult cases, diagnostic tests used in the suppression of aldosterone secretion 9a-ftorkortizolom (kortinefom). Within 3... Read more »
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When Aldo steron producing adrenal tumor shows adrenalectomy (removal of the tumor together with suprarenalopathy). Unambiguous opinion about the choice of treatment for bilateral adrenal hyperplasia is not, usually applied conservative therapy (veroshpiron, potassium preparations, antihypertensives).
In severe diffuse nodular hyperplasia, a significant increase in functional activity of one of the adrenal glands, failure of conservative therapy is possible... Read more »
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